Defects in developing frog brain can be prevented or repaired with bioelectric drugs

(Tufts University) Researchers discovered that the brains of developing frog embryos damaged by nicotine exposure can be repaired by treatment with certain drugs -- ionoceuticals -- that drive the recovery of bioelectric patterns in the embryo, followed by repair of normal anatomy, gene expression and brain function in the growing tadpole. The research could provide a roadmap for the exploration of therapeutic drugs to help repair birth defects.